Acquired Immune Deficiency Syndrome (AIDS) was recognized in
1981 as a new syndrome capable of destroying the human beings. The sudden
appearance of the epidemic among previously known rare diseases was soon
recognized on the basis of its association with immune- suppressant
characteristics, henceforth unrecorded in human history.
The alarming incidence of HIV exposure in Asia was a source of
motivation to find out some real effective anti-HIV drug from indigenous
traditional medicines / plants resources. The World Health Organization (WHO) was contacted in this respect
and our Drug Abuse Treatment Center at Karachi was listed with WHO , was the
only Government recognized center engaged in research on Drug Abuse AIDS
Treatment in Pakistan at that time.
In 1994, a Medical Research Collaborative Project was initiated
between the Ministry of Health, Government of Japan and Pakistan, entitled:
“Epidemiological Studies on Viral Infections through Blood Transfusion in Asian
Countries” for which Dr. Muhammad Rafiq and later on Dr. Asim Awan were
selected as members of the Project by the Japanese Government. Nagoya
University, School of Medicine Under this project, Government of Japan
offered to extend the research facilities for anti HIV drug screening.
To verify the effects of highly bioactive extract in human, a
clinical trial was initiated in accordance with the ICH-GCP guidelines and in
consultation with the Japanese Collaborators ,
after obtaining the informed consent from HIV / AIDS patients. A thorough
physical examination was carried out, of each trial case.
The laboratory tests were performed in the Aga khan Univesity Hospital.
The HIV antibody ( ELISA ) positive / Western Blot positive individuals were
treated with this extract that had shown great promise in in
vitro studies. The
results are presented in graphical form.
The drug was administered to 31 HIV / AIDS patients with a
marked degree of success and remarkable improvement in constitutional symptoms.
Twenty Six (26) individuals showed full recovery and their virus load was found
below quantitation limits or HIV-RNA not detected by PCR, (both quantitative
and qualitative). This success was achieved in most of the patients within 6 to
18 months of the treatment
This drug carries a hope and message of health to the HIV / AIDS
patients all over the world. It is cost effective and easily administered
orally in capsule form; it is a patients friendly drug having no side effects.
The drug works slowly but definitely bringing the viral load from high to low
and finally to non-detectable levels.
In the event of either poor drug compliance or discontinuity in
administration of the drug by the patients, the effectiveness of the drug was
not found impaired. This magic drug is equally effective against HIV-1/HIV-2
and all HIV clades (sub-types) as proven through in vitro studies.
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